Cushing’s disease in dogs occurs when the adrenal glands produce excess cortisol in the dog’s body. Cortisol is a hormone produced by the adrenal glands to help respond to stress, regulate blood sugar, and fight infections. Cushing's disease is also known as Hyperadrenocorticism.
Cushing’s disease in dogs mainly occurs when there is a benign or malignant tumor in the pituitary gland or the adrenal gland in some rare cases. It primarily affects middle-aged to old dogs.
Symptoms of Cushing's disease in your dog include excessive panting, increased thirst, excess hunger, lethargy, developed potbelly, frequent urinating, hair loss, and thinning skin. It is always advisable to visit your veterinarian for some tests.
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The good news is that even if the results read positive, research has proven that a combination of Lignans and melatonin provides you with a solution to Cushing’s disease without the risk of side effects. Both Lignans and Melatonin can be used separately to treat Cushing’s disease but it is highly recommended for them to be used together.
The combination of lignans with melatonin is the best first treatment for Cushing's disease since they are both natural substances and less costly compared to other synthetic drugs and treatments. Our Lignans and Melatonin combination are carefully formulated to ensure that the correct amount of each supplement is properly placed for optimum therapeutic effect.
Using Lignans and Melatonin together helps to lower the production of aromatase enzyme which in turn helps to lower estradiol and cortisol concentrations. Estradiol is the hormone responsible for Cushing’s symptoms. They also help to reduce the pain caused by the disease. The combination does not affect aldosterone concentration.
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A combination of Lignans and Melatonin act directly on the adrenal tumor cells. This natural remedy has been proven to be very gentle on your dog. Flaxseed lignans have a medicinal property for dogs suffering from this uncomfortable disease. They are high in fiber which helps to promote colon health. Lignans are available as HMR lignans or SDG lignans.
Since Lignans and Melatonin are made from natural ingredients, the combination helps to safely reduce the unpleasant symptoms of Cushing’s disease with no risk of serious side effects.
Lignans dosage for Cushing's is 1-2 mg of lignan per pound of body weight.
Melatonin also helps to treat hair loss in dogs, especially for those with Cushing’s disease. It also lowers cortisol levels. Melatonin dosage for Cushing's is 3mg every 12 hours for dogs under 30 Ibs and 6mg every 12 hours for dogs over 30 Ibs. People who have used this combination of Lignans with Melatonin on their dogs have reported visible results within the first four months.
The Melatonin and Lignans Combo can be given safely with the Prana Pets Cushing's Killer Combo for a well-rounded, natural way to help ease your dog's Cushing's symptoms.