✓ Verified Purchase
★★★★★
Noticeable difference in weeks
After about three weeks I started seeing real changes in my dog's energy and coat. She's more like herself again, bright-eyed and interested in things. I'll keep buying this.
Prana Pets · Cushing's Support
Adrenal and Lignans Combo
Natural Hormone & Cortisol Support
Support your dog's adrenal and pituitary glands, help maintain balanced cortisol levels, and promote overall hormonal wellness with this veterinarian-formulated liquid blend. Easy to administer, naturally sourced, made in the USA.
- Supports healthy adrenal function
- Helps maintain normal cortisol
- Promotes hormonal balance
- Supports immune wellness
- Helps maintain energy
- Supports coat & vitality
FREE shipping with 2+ bottles
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Vet
Formulated -
365-Day
Guarantee -
Made in
USA -
10,000+
Pet Parents
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Book →Why Pet Parents Love It
Real support, in every dropper.
Adrenal and Lignans Combo was formulated to address the things pet parents care about most: healthy hormones, balanced cortisol, and a dog who feels like themselves again.
Balanced cortisol levels
Helps maintain cortisol in the body's natural range, the hormone at the center of adrenal wellness.
Healthy adrenal function
Targeted botanical support for the adrenal and pituitary glands, so they can do their job without extra strain.
Everyday vitality
Supports the small daily signs of a well dog: steady energy, healthy coat, and overall quality of life.
Immune system balance
Supports a well-regulated immune response, because adrenal health and immunity are deeply connected.
Hormonal stability
Naturally sourced ingredients traditionally used to help the body maintain its hormonal rhythm.
Liquid = easier dosing
No chasing pills or wrestling tablets. Drop it on food or directly in the mouth - done.
How To Use
Easy to give, easy to love.
Three steps. One happy dog. Consistency is what makes the difference, a daily habit is easier than you'd think.
Shake well
A quick shake ensures the botanicals are evenly distributed in the dropper.
Dose by weight
Use the included dropper. Dosage guidelines are on the bottle and in every order.
Add to food or mouth
Drop directly into the mouth, or mix into food or a treat, twice daily.
The Formula
Every ingredient,
chosen with intention.
Naturally sourced, traditionally used, and put together by veterinarians who understand canine wellness.
Astragalus Root
Astragalus membranaceusTraditionally used to support the body's adaptive stress response and immune system balance.
Holy Basil
Ocimum tenuiflorumA classic adaptogen revered for supporting healthy cortisol levels and hormonal wellness.
Ashwagandha
Withania somniferaA well-studied adaptogenic root used to support adrenal function and overall vitality.
Milk Thistle
Silybum marianumSupports the liver, which works alongside the adrenal and pituitary glands to maintain balance.
Reviews
Loved by dogs, trusted by their humans.
Real reviews from verified pet parents. No edits, no cherry-picking. Just the stories of dogs feeling like themselves again.
4.7
244 reviews
✓ Verified Purchase
★★★★★
Easy to give, dog doesn't fuss
The liquid is so much easier than pills. My dog takes it right on her food, no drama. Support team was also amazing when I called with dosing questions.
✓ Verified Purchase
★★★★★
Part of our daily routine now
I ordered this after reading about adrenal support. It's become part of our daily routine alongside what our vet recommended. Combined, we've seen our pup thriving again.
Questions, Answered
Everything pet parents usually ask.
How long before I see results?
Most pet parents notice subtle changes within 3–4 weeks of consistent daily use. Because adrenal support is about long-term balance, the best results typically show up between weeks 4 and 8. If you're not satisfied, our 365-day money-back guarantee has you covered.
Can I give this with my dog's current medications?
Adrenal Balance shouldn't interfere with most prescription medications, but every situation is different. We always recommend speaking with your veterinarian before combining supplements with any prescribed treatment. Our free consult line is also here to help you think it through.
How do I dose for my dog's weight?
Full dosing guidelines are printed on every bottle and included with your order. As a general reference, most dogs receive 2 doses per day, with the amount scaled by body weight. If your dog is very small or very large, a quick call with our team can dial it in exactly.
Are there any side effects?
Adrenal Balance is formulated with naturally sourced ingredients and is generally well-tolerated. As with any new supplement, introduce it gradually and watch for any unusual reactions. Always cross-check ingredients against your dog's known allergies.
What's your return policy?
Every Prana Pets product comes with a 365-day money-back guarantee. If it's not helping, send it back for a full product refund — even if the bottle's empty. We want you to feel great about your purchase for a full year.
How long does one bottle last?
A single bottle generally lasts around 30 days for most medium-sized dogs. Smaller dogs may get 45–60 days per bottle, while larger breeds may go through one a bit faster. Two- and three-bottle packs are our most popular picks for uninterrupted support.
If it's not helping your dog, send it back.
We stand behind every bottle of Adrenal and Lignans Combo with a full 365-day money-back promise. No hoops, no fine print. Just a team that genuinely wants your dog to feel better. Take the year. See how it goes. If you're not happy, we'll refund you. That simple.
Your Next Step
Give your dog the support they deserve.
Adrenal and Lignans Combo is a small daily habit that can make a real difference. Try it risk-free for a full year, we'll be here if you need us.
Shop Adrenal and Lignans ComboImportant Notice
This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your veterinarian regarding your dog's health. Statements on this page have not been evaluated by the U.S. Food and Drug Administration.